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28th Hawaii International Conference on System Sciences (HICSS'95)   p. 62
A database for globin gene expression data
W. Miller, Dept. of Comput. Sci. & Eng., Pennsylvania State Univ., University Park, PA, USA
A. Elsherbini, Dept. of Comput. Sci. & Eng., Pennsylvania State Univ., University Park, PA, USA
J. Peck, Dept. of Comput. Sci. & Eng., Pennsylvania State Univ., University Park, PA, USA
C. Riemer, Dept. of Comput. Sci. & Eng., Pennsylvania State Univ., University Park, PA, USA
S. Schwartz, Dept. of Comput. Sci. & Eng., Pennsylvania State Univ., University Park, PA, USA
N. Stojanovic, Dept. of Comput. Sci. & Eng., Pennsylvania State Univ., University Park, PA, USA
R. Hardison, Dept. of Comput. Sci. & Eng., Pennsylvania State Univ., University Park, PA, USA

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DOI Bookmark: http://doi.ieeecomputersociety.org/10.1109/HICSS.1995.375350
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Abstract
We describe a prototype database of sequence alignments and experimental results for the /spl beta/-like globin gene cluster of mammals. This data repository is intended to help the international community of globin gene biologists to plan experiments, to design models and, ultimately, to understand regulation of those genes. Moreover, the approaches and software developed for this project will be applicable to other sequence-analysis problems. Our first steps were to develop a program that can simultaneously align a few very long sequences and to establish an e-mail server that formats any requested portion of the alignment, annotated to indicate highly conserved regions and known run sequence features. We are currently developing a World-Wide Web server that will provide access to the wealth of pertinent experimental data, in register with the annotated alignment, through a variety of query languages and graphical presentations.
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Index Terms- genetics; biology computing; database management systems; electronic mail; information networks; globin gene expression database; prototype database; sequence alignments; experimental results; /spl beta/-like globin gene cluster; mammals; data repository; globin gene biologists; regulation; sequence-analysis problems; e-mail server; highly conserved regions; run sequence features; World-Wide Web server; annotated alignment; query languages; graphical presentations Citation:  W. Miller, A. Elsherbini, J. Peck, C. Riemer, S. Schwartz, N. Stojanovic, R. Hardison, "A database for globin gene expression data," hicss, p. 62,  28th Hawaii International Conference on System Sciences (HICSS'95),  1995